The chances of getting the corona virus through the three-dose MRNA vaccine are just 1.8% and the two doses are 6.6%.
The third dose reduces the chances of contracting the virus by 86% compared to two vaccine doses.
The results of a study conducted by Maccabee Health Services in Tel Aviv in collaboration with Yale University in the United States were published in the scientific journal JAMA.
More than 306,000 people over the age of 40 were vaccinated with 2 or 3 doses of MRNA in this study and were negative for the corona virus before the follow-up began, which lasted from August 1 to October 4, 2021.
During this period, 500,232 molecular trials were performed, of which 227,380 were vaccinated with 2 doses and 272,852 with 3 doses. Positive results (i.e. corona virus infection) were recorded in 14,989 subjects in the two dose group (6.6%) and 4,941 subjects in the third dose group (1.8%).
The positive rate was higher in those who did not take the booster dose and in those who took the third dose in the previous 7 days and lower in those who took the third dose 2 weeks ago.
The margin measure of effectiveness of the third dose increased over time after taking the booster, with a slight reduction in the chances of a positive test in the first 7 days (12%), moderate marginal performance on days 7 to 13 (58%) and 14 to 20 days thereafter (85). %) High level of performance. After repeating this analysis individually for each age group, estimates for the margin effect will be proportional to all ages after the first 2 weeks. Similarly, the estimates were the same regardless of whether other similar diseases preceded it.
Compared with the second booster, the chances of a negative test after the booster dose increased from 50% to 71% at 6 days after the booster dose, to 71% at 7–13 days after the booster dose, and to 87% at 14 to 20 days. 85% in 21 to 27 days and 83% in 28 – 65 days.
Finally, the chances of hospitalization were estimated between those who received the booster vaccine and those who received 2 doses. After 14 days, those receiving the booster dose had a 92% to 97% lower chance of hospitalization than those receiving only the 2 dose. Explaining these assessments of hospitality is challenging. However, the apparent immune response to booster became apparent a few days after ingestion (87% efficacy in 0–6 days).
